How effective Quetiapine at preventing relapse?

1) One group of studies looked at how effective quetiapine is at preventing any type of relapse.

When comparing people taking quetiapine versus people taking no medication, these studies show that:

  • ANY TYPE OF RELAPSE

    QUETIAPINE
    77 in 100
    people taking quetiapine will NOT RELAPSE within 1 up to 2 years
    23 in 100
    people will RELAPSE
    NO MEDICATION
    53 in 100
    people taking no medication will NOT RELAPSE within 1 up to 2 years
    47 in 100
    people will RELAPSE

2) Another group of studies looked at how effective quetiapine is at preventing relapse into depression.

When comparing people taking quetiapine versus people taking no medication, these studies show that:

  • RELAPSE INTO DEPRESSION

    QUETIAPINE
    89 in 100
    people taking quetiapine will NOT RELAPSE into depression within 1 up to 2 years
    11 in 100
    people will RELAPSE into depression
    NO MEDICATION
    75 in 100
    people taking no medication will NOT RELAPSE into depression within 1 up to 2 years
    25 in 100
    people will RELAPSE into depression

3) Another group of studies looked at how effective quetiapine is at preventing relapse into hypomania.

When comparing people taking quetiapine versus people taking no medication, these studies show that:

  • RELAPSE INTO HYPOMANIA

    QUETIAPINE
    88 in 100
    people taking quetiapine will NOT RELAPSE into hypomania within 1 up to 2 years
    12 in 100
    people will RELAPSE into hypomania
    NO MEDICATION
    78 in 100
    people taking no medication will NOT RELAPSE into hypomania within 1 up to 2 years
    22 in 100
    people will RELAPSE into hypomania
Studies show that quetiapine appears to be better than no medication at preventing all types of relapse. It appears to be good at preventing both depression and hypomania relapse.

A meta-analysis based on RCT studies of relapse in people with bipolar I and II disorders from 3 months up to 3 years (Quetiapine doses 300-800mg/day).